Robert W Gereau Selected Research

fenobam

1/2020	The metabotropic glutamate receptor 5 negative allosteric modulator fenobam: pharmacokinetics, side effects, and analgesic effects in healthy human subjects.
3/2012	Metabotropic glutamate receptor 5 (mGluR5) regulates bladder nociception.
12/2011	Metabotropic glutamate receptor 5 antagonism with fenobam: examination of analgesic tolerance and side effect profile in mice.
9/2009	The metabotropic glutamate receptor subtype 5 antagonist fenobam is analgesic and has improved in vivo selectivity compared with the prototypical antagonist 2-methyl-6-(phenylethynyl)-pyridine.

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Robert W Gereau Research Topics

Disease

50	Pain (Aches) 01/2022 - 08/2002
18	Inflammation (Inflammations) 12/2022 - 09/2002
17	Hypersensitivity (Allergy) 03/2018 - 10/2004
13	Hyperalgesia 01/2022 - 08/2002
11	Neuralgia (Stump Neuralgia) 01/2018 - 01/2006
9	Chronic Pain 01/2018 - 01/2007
3	Pruritus (Itching) 01/2022 - 04/2015
3	Visceral Pain 10/2017 - 05/2011
2	Migraine Disorders (Migraine) 12/2014 - 07/2011
2	Weight Gain 12/2011 - 11/2010
1	Wounds and Injuries (Trauma) 12/2022
1	Virus Diseases (Viral Diseases) 12/2022
1	Atopic Dermatitis (Atopic Eczema) 01/2022
1	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 10/2020
1	Diarrhea 10/2020
1	Medically Unexplained Symptoms 10/2020
1	Ganglion Cysts (Ganglion) 01/2020
1	Mood Disorders (Mood Disorder) 01/2019
1	Tuberous Sclerosis (Bourneville's Disease) 03/2018
1	Postherpetic Neuralgia 01/2018
1	Pelvic Pain 10/2017
1	Cystitis 10/2017
1	Cold Hypersensitivity 03/2015
1	Interstitial Cystitis (Interstitial Cystitis, Chronic) 05/2014
1	Fibromyalgia (Fibrositis) 05/2014
1	Parkinson Disease (Parkinson's Disease) 10/2013
1	Pyuria 01/2013
1	Aneurysm (Aneurysms) 07/2011
1	Headache (Headaches) 07/2011

Drug/Important Bio-Agent (IBA)

13	Analgesics (Analgesic Drugs)IBA 01/2020 - 01/2007
13	Formaldehyde (Formol)FDA Link 01/2015 - 01/2006
8	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 01/2016 - 01/2003
7	Freund's AdjuvantIBA 08/2017 - 09/2004
6	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 08/2013 - 09/2004
4	fenobamIBA 01/2020 - 09/2009
4	Pharmaceutical PreparationsIBA 01/2020 - 06/2006
4	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 08/2013 - 09/2004
3	Capsaicin (Zostrix)FDA Link 01/2020 - 01/2013
3	Opioid Analgesics (Opioids)IBA 01/2019 - 09/2007
3	Ion Channels (Ion Channel)IBA 01/2018 - 10/2004
3	Dinoprostone (PGE2)FDA Link 01/2016 - 08/2002
3	Metabotropic Glutamate 5 ReceptorIBA 10/2012 - 09/2002
3	Glutamic Acid (Glutamate)FDA Link 04/2010 - 09/2002
3	TRPV Cation ChannelsIBA 01/2006 - 08/2002
2	Chloroquine (Aralen)FDA LinkGeneric 01/2021 - 04/2015
2	PlasticsIBA 01/2019 - 01/2003
2	metabotropic glutamate receptor 2IBA 03/2018 - 06/2006
2	Angiotensin IIIBA 01/2018 - 01/2018
2	Type 2 Angiotensin ReceptorIBA 01/2018 - 08/2017
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 10/2017 - 09/2011
2	Protein Isoforms (Isoforms)IBA 06/2015 - 08/2010
2	3,4-dihydroxyphenylglycolIBA 06/2010 - 09/2004
2	U 0126 (UO 126)IBA 06/2008 - 09/2004
2	Serotonin (5 Hydroxytryptamine)IBA 05/2007 - 12/2006
2	Acetylcarnitine (Alcar)IBA 01/2007 - 06/2006
1	naphthalen- 1- yl- (4- pentyloxynaphthalen- 1- yl)methanoneIBA 01/2022
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 01/2022
1	Interleukin-33IBA 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Immunoglobulin A (IgA)IBA 10/2020
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2020
1	Dynorphins (Dynorphin)IBA 01/2019
1	Mechanistic Target of Rapamycin Complex 1IBA 03/2018
1	Angiotensin Receptors (Angiotensin II Receptor)IBA 01/2018
1	AngiotensinsIBA 01/2018
1	Non-Narcotic Analgesics (Analgesics, Non Narcotic)IBA 01/2018
1	AntibodiesIBA 10/2017
1	Neutralizing AntibodiesIBA 10/2017
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2017
1	PD 123319IBA 08/2017
1	AcetoneIBA 04/2015
1	Ether (Diethyl Ether)IBA 04/2015
1	Irritants (Vesicants)IBA 12/2014
1	AntipainIBA 12/2014
1	Histone Deacetylase InhibitorsIBA 11/2014
1	Biological ProductsIBA 09/2014
1	Narcotics (Narcotic Analgesics)IBA 05/2014
1	Dopamine (Intropin)FDA LinkGeneric 10/2013
1	CalciumIBA 08/2013
1	Histamine (Histamine Dihydrochloride)FDA Link 06/2013
1	Gabapentin (Neurontin)FDA LinkGeneric 01/2013
1	LipopolysaccharidesIBA 01/2013
1	Protamines (Protamine Sulfate)FDA Link 01/2013
1	imidazoleIBA 03/2012
1	N-Methylaspartate (NMDA)IBA 03/2012
1	Urea (Carbamide)FDA LinkGeneric 03/2012
1	Morphine (MS Contin)FDA LinkGeneric 01/2012
1	IsoenzymesIBA 12/2011
1	Protein Kinase CIBA 12/2011

Therapy/Procedure

10	Analgesia 01/2022 - 06/2006
6	Therapeutics 09/2018 - 03/2008
2	Drug Therapy (Chemotherapy) 12/2022 - 01/2007
1	Electrodes (Electrode) 01/2019
1	Cell Transplantation 01/2018
1	Denervation 01/2015
1	Transcutaneous Electric Nerve Stimulation (TENS) 12/2014
1	Injections 08/2013
1	Bite Force (Occlusal Forces) 08/2013
1	Ligation 01/2012
1	Stents 07/2011